KORELASI HASIL UJI WIDAL DENGAN RAPID TEST IgG DAN IgM PADA PASIEN SUSPEK DEMAM TIFOID
DOI:
https://doi.org/10.51878/healthy.v5i4.14121Keywords:
Demam Tifoid, uji widal, Rapid TestAbstract
Typhoid fever is a systemic infectious disease caused by Salmonella enterica serovar Typhi and requires laboratory examinations to support diagnosis. The Widal test and IgG/IgM rapid test are serological examinations that are still widely used in healthcare facilities, but they have different test characteristics. This study aimed to analyze the correlation between Widal test results and IgG and IgM rapid test results in patients with suspected typhoid fever at Dr. H. Moh. Anwar Regional General Hospital, Sumenep. This study employed an analytical observational design with a cross-sectional approach and purposive sampling technique. The study was conducted from February 2 to 28, 2026, involving 35 patients with suspected typhoid fever. The examinations included the slide agglutination Widal test and immunochromatographic IgG/IgM rapid test. Data were analyzed using Spearman's correlation test with a significance level of p < 0.05. The results showed a significant correlation between the Widal test and the IgG rapid test, with a correlation coefficient of r = 0.667 and p < 0.001, indicating a strong positive correlation. A significant correlation was also found between the Widal test and the IgM rapid test, with r = 0.861 and p < 0.001, indicating a very strong positive correlation. In conclusion, there was a significant correlation between Widal test results and both IgG and IgM rapid test results in patients with suspected typhoid fever. These findings indicate an association between the results of the two serological examinations; however, their interpretation should consider the patient's clinical condition and the stage of disease progression.
ABSTRAK
Demam tifoid merupakan penyakit infeksi sistemik yang disebabkan oleh Salmonella enterica serovar Typhi dan memerlukan pemeriksaan penunjang untuk membantu diagnosis. Uji Widal dan rapid test IgG/IgM merupakan pemeriksaan serologis yang masih digunakan di fasilitas pelayanan kesehatan, tetapi memiliki karakteristik pemeriksaan yang berbeda. Penelitian ini bertujuan menganalisis korelasi hasil uji Widal dengan rapid test IgG dan IgM pada pasien suspek demam tifoid di RSUD Dr. H. Moh. Anwar Sumenep. Penelitian menggunakan desain observasional analitik dengan pendekatan cross-sectional dan teknik purposive sampling. Penelitian dilaksanakan pada 2–28 Februari 2026 dengan jumlah sampel sebanyak 35 pasien suspek demam tifoid. Pemeriksaan dilakukan menggunakan uji Widal metode slide aglutinasi dan rapid test IgG/IgM metode imunokromatografi. Data dianalisis menggunakan uji korelasi Spearman dengan tingkat kemaknaan p < 0,05. Hasil penelitian menunjukkan terdapat korelasi signifikan antara hasil uji Widal dengan rapid test IgG dengan koefisien korelasi r = 0,667 dan p < 0,001 yang menunjukkan hubungan kuat. Korelasi antara hasil uji Widal dengan rapid test IgM juga signifikan dengan r = 0,861 dan p < 0,001 yang menunjukkan hubungan sangat kuat. Dengan demikian, terdapat korelasi signifikan antara hasil uji Widal dengan rapid test IgG dan IgM pada pasien suspek demam tifoid. Hasil tersebut menunjukkan adanya keterkaitan antara hasil kedua pemeriksaan serologis, tetapi interpretasinya tetap perlu mempertimbangkan kondisi klinis dan fase perjalanan penyakit.
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