GAMBARAN JAMUR CANDIDA ALBICANS DALAM URINE PASIEN DIABETES MELITUS
DOI:
https://doi.org/10.51878/healthy.v5i4.15730Keywords:
Candida albicans, diabetes melitus, kandiduriaAbstract
Diabetes mellitus may increase susceptibility to fungal colonization of the urinary tract, particularly when hyperglycemia is accompanied by glucosuria and impaired host defenses. Therefore, detecting Candida albicans in urine is important for describing the potential occurrence of candiduria in patients with diabetes mellitus. This study aimed to identify the presence of Candida albicans in urine samples from patients with diabetes mellitus at Syarifah Ambami Rato Ebu Regional General Hospital, Bangkalan. A descriptive study with a laboratory observational approach was conducted from March 2 to April 30, 2026. Twenty urine samples were selected using purposive sampling based on random blood glucose levels above 200 mg/dL or fasting blood glucose levels above 125 mg/dL. Identification involved culture on Sabouraud Dextrose Agar (SDA), microscopic examination using Lactophenol Cotton Blue (LPCB) staining, and a germ tube test. The results showed that 4 samples (20%) were positive for Candida albicans, whereas 16 samples (80%) were negative. All positive samples were obtained from female patients. In conclusion, Candida albicans was detected in a proportion of urine samples from patients with diabetes mellitus. These findings provide preliminary information on its presence but do not establish a causal relationship between hyperglycemia and candiduria.
ABSTRAK
Diabetes melitus dapat meningkatkan kerentanan terhadap kolonisasi jamur pada saluran kemih, terutama ketika hiperglikemia disertai glukosuria dan gangguan pertahanan tubuh. Oleh karena itu, pemeriksaan keberadaan Candida albicans dalam urine diperlukan untuk memperoleh gambaran awal potensi kandiduria pada pasien diabetes melitus. Penelitian ini bertujuan mengidentifikasi keberadaan Candida albicans dalam urine pasien diabetes melitus di RSUD Syarifah Ambami Rato Ebu Bangkalan. Penelitian menggunakan desain deskriptif dengan pendekatan observasional laboratorium pada 2 Maret–30 April 2026. Sebanyak 20 sampel urine dipilih menggunakan teknik purposive sampling berdasarkan kriteria kadar Glukosa Darah Acak (GDA) >200 mg/dL atau Glukosa Darah Puasa (GDP) >125 mg/dL. Identifikasi dilakukan melalui kultur pada media Sabouraud Dextrose Agar (SDA), pemeriksaan mikroskopis menggunakan pewarnaan Lactophenol Cotton Blue (LPCB), dan uji germ tube. Hasil pemeriksaan menunjukkan bahwa 4 sampel (20%) positif Candida albicans, sedangkan 16 sampel (80%) negatif. Seluruh sampel positif berasal dari pasien perempuan. Penelitian ini menyimpulkan bahwa Candida albicans ditemukan pada sebagian sampel urine pasien diabetes melitus. Temuan ini memberikan gambaran awal keberadaan jamur tersebut, tetapi belum membuktikan hubungan sebab-akibat antara hiperglikemia dan kandiduria.
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